Connexin 43 Controls the Astrocyte Immunoregulatory Phenotype
نویسندگان
چکیده
منابع مشابه
Fluoxetin Upregulates Connexin 43 Expression in Astrocyte
Introduction: Recent studies have shown that astrocytes play major roles in normal and disease condition of the central nervous system including multiple sclerosis (MS). Molecular target therapy studies in MS have revealed that connexin-43 (Cx43) and Aquaporin-4 (AQP4) contents of astrocytes undergo expression alteration. Fluoxetine had some effects in MS patients unrelated to its known antidep...
متن کاملfluoxetin upregulates connexin 43 expression in astrocyte
introduction: recent studies have shown that astrocytes play major roles in normal and disease condition of the central nervous system including multiple sclerosis (ms). molecular target therapy studies in ms have revealed that connexin-43 (cx43) and aquaporin-4 (aqp4) contents of astrocytes undergo expression alteration. fluoxetine had some effects in ms patients unrelated to its known antidep...
متن کاملFluoxetin Upregulates Connexin 43 Expression in Astrocyte
INTRODUCTION Recent studies have shown that astrocytes play major roles in normal and disease condition of the central nervous system including multiple sclerosis (MS). Molecular target therapy studies in MS have revealed that connexin-43 (Cx43) and Aquaporin-4 (AQP4) contents of astrocytes undergo expression alteration. Fluoxetine had some effects in MS patients unrelated to its known antidepr...
متن کاملConnexin 43 controls the multipolar phase of neuronal migration to the cerebral cortex.
The prospective pyramidal neurons, migrating from the proliferative ventricular zone to the overlaying cortical plate, assume multipolar morphology while passing through the transient subventricular zone. Here, we show that this morphogenetic transformation, from the bipolar to the mutipolar and then back to bipolar again, is associated with expression of connexin 43 (Cx43) and, that knockdown ...
متن کاملReversion of the Neoplastic Phenotype of Human Glioblastoma Cells by Connexin 43 (CX43)1
Connexins (ex), structural components of gap junction, are believed to play a role in the regulation of cell proliferation and suppression of the neoplastic phenotype. We used human brain glioblastoma tumor cells as a model system to test this hypothesis. Western blot and reverse tran scription-PC K analysis indicate that the expression levels of the gap junction protein connexin 43 (cx43) are ...
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ژورنال
عنوان ژورنال: Brain Sciences
سال: 2018
ISSN: 2076-3425
DOI: 10.3390/brainsci8040050